On July 12, 2016, The National Institute of Health awarded Intact Genomics a Small Business Innovation Research (SBIR) second Phase II grant to further develop the patent-pending fungal artificial chromosome (FAC) technology. The new study’s intent is to activate silent and cryptic fungal biosynthetic gene clusters for natural product discovery by a superior ‘FAC recombineering and transgenic animal-like’ system in Aspergillus nidulans.